PREDICT Latent TB Study

The UK Prognostic Study of the Interferon Gamma Release Assay for Tuberculosis (PREDICT)

Welcome to the website for the PREDICT study, which will look at the tests that are available for diagnosing people with tuberculosis, TB. This study is funded by the NIHR HTA Programme and coordinated by Public Health England.  We are working in NHS sites, clinics, GP surgeries and community settings to investigate prognostic value of tests for latent tuberculosis infection.

TB is a disease which can take a long time to develop after a person is infected with the bacteria. The time between infection and becoming ill with symptoms of TB is called the latent period. During the latent period, some people manage to beat the infection and do not go on to have symptoms, but other people do go on to become ill. The tests that we have at the moment are not able to tell us who will become ill and who won’t. In this study we will be looking at some new tests that may help to do this so that we don’t treat people who will stay well, especially because some of the TB treatments have some side effects.

We have now completed the study. Our results will be published soon in the Lancet Infectious Diseases and in the NIHR HTA journal.


Our academic partners include

University College London

Imperial College

University of Birmingham

Queen Mary University of London

Brunel University